Since its launch in June 2014, the impetus for openFDA has been to make it easier to get access to publicly available FDA data. FDA’s goal is to make it simple for an application, mobile device, web developer, or researcher to use data from FDA.
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Maternal History of Childhood Abuse and Risk of Asthma and Allergy in 2-Year-Old Children. Tomfohr-Madsen LM1, Bayrampour H, Tough S. Author information Abstract OBJECTIVES: Exposure to child abuse (CA) is associated with an increased risk of developing asthma and allergies; it is unknown if that risk is present across generations. This study investigated if 2-year-old children born to mothers with a history of CA were at an increased risk of receiving a diagnosis of asthma or allergies. METHODS: Data from 1,551 participants were collected as part of the All Our Babies (AOB) study, a prospective pregnancy cohort. During pregnancy, each woman provided information about her own history of CA, and at 24 months postpartum, she provided information about her child's medical diagnoses. Symptoms of maternal depression and anxiety were assessed during pregnancy and at 24 months postpartum. RESULTS: Unadjusted models showed that compared to children born to mothers without a history of CA, 2-year-old children born to mothers with a history of CA were more likely to have had a diagnosis of asthma (7.4% vs 4.2%, p = .016) or allergy (15.6% vs 9.2%, p < .001). Maternal symptoms of depression assessed in late pregnancy and symptoms of depression and anxiety at 24 months postpartum were significant mediators of the relationship between maternal CA and 2-year-old asthma diagnosis. Maternal symptoms of depression and anxiety assessed in late pregnancy were also significant mediators of the relationship between maternal CA and 2-year-old allergy diagnosis. CONCLUSIONS: The results indicate that maternal exposure to CA is associated with increased risk of asthma and allergy in their 2-year-old children; symptoms of maternal depression and anxiety were identified as pathways linking the variables. PMID: 27763990 DOI: 10.1097/PSY.0000000000000419
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The paper by Bolland et al.1 in this issue had a longer “gestation” than usual at Neurology®; it was received on December 4, 2015. We usually review on a tight timeline and publish important work quickly. But this manuscript has a different focus as it presents a statistical analysis that demonstrates probable scientific misconduct (fraud) on a large scale.
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A new study suggests probable scientific misconduct in at least some of 33 bone health trials published in various medical journals.
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Throughout the last few decades, diseases that spill over from animals to humans have been on the rise. What’s behind their increase, and can we do anything to combat these dangerous foes? Join scientists as they investigate the rise of spillover viruses like Zika, Ebola and Nipah, and learn what science can do to anticipate and prevent epidemics around the world.
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WHO Global Surge Training: Testing the “new skeleton” of WHO emergency operations
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The global population of wild animals has declined 60 per cent since 1970 and is set to drop another seven per cent by 2020 due to human impact on the environment, according to a WWF report.
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SOS Telemedicina cursos en línea cuenta con el apoyo de profesionales de la medicina, especialistas en diversas áreas de la salud, capacitados para ofrecer información validada científicamente en apoyo al personal de salud y a la comunidad, haciendo énfasis en la embarazada, las madres, los niños y los adolescentes.
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Best Essential international mental health resources
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A novel population-based health index was identified, in addition to calculation of the rates of psychiatric disorder in a random sample from a large urban centre.
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A short audio visual tutortial that provides basic understanding of central nervous system reflexes.
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Since human beings have encounted stimulants, we have been fascinated by the potential effects of substances on cognitive function, memory, and intelligence, as,for example, exemplified in the theme of the film "Limitless". Currently, brain imaging is being used to market supplements that supposedly enhance brain function, memory, and, by implication, intelligence. This is the essence of positivism in a reductionist approach to scientific inquiry. Accordingly, increased brain activity is equivalent to more or better use of the brain somehow and that the absence of activity is equivalent to less effective brain function. Aside from the evidence indicating that the brain can metabolize glucose anaerobicly, as do muscles, who is to say that the surface of the brain does not act more like the retina in terms of integrating in transmitting the signals from impinging light frequencies to the visual cortex: signalling to the brain from the retina is based on inhibition of intrinsic activity. In essence what we see is sculpted by what gets turned off. This was suggested by Pribram in the early 70s as a mechanism by which information enters consciousness. Taking a drug to general increase activity in the brain in a non-specific way has nothing to do with intelligence, and while overall capacity might increase in a transient way, while a drug is active, history has shown us that there is invariably a downside to using stimulants as cognitive enhancers.
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A global network for learning about integrated people-centred health services.
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Claudio, Thank you for helping to make ABMS Conference 2016 a success!
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The Framework on integrated people-centred health services is a call for a fundamental shift in the way health services are funded, managed and delivered. Globally, more than 400 million people lack access to essential health care.
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